Hunger Hormone Affects Alcohol Intake

X-ray of human body

A new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) provides further evidence that a hormone produced in the stomach influences alcohol consumption in humans. As reported in Molecular Psychiatry, researchers led by Lorenzo Leggio, M.D., Ph.D., demonstrated that the hormone, called ghrelin, may be a promising target for developing … Read more

MicroRNAs May Have Therapeutic Potential for Alcohol-Induced Liver Injury

Picture of DNA strand

MicroRNAs, or miRNAs, are short strands of RNA that play important roles in gene regulation. In two recent studies, researchers supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) identified two miRNAs that may help protect against alcohol-induced liver injury. Paramananda Saikia, Ph.D., and colleagues at the Cleveland Clinic, in studies conducted in … Read more

Behavioral Interventions That Address Alcohol Use Help People Living With HIV/AIDS

Doctor speaking to a patient

There are more than 36 million people living with HIV/AIDS (PLWHA) worldwide. Alcohol misuse is a significant concern for this population because it contributes to risky sexual behavior, reduces adherence to HIV medication regimens, and exacerbates other health conditions. Interventions that address alcohol misuse among PLWHA have the potential to help improve their health outcomes. … Read more

Rehabilitating the Addicted Brain With Transcranial Magnetic Stimulation

Recent studies have highlighted the potential of transcranial magnetic stimulation (TMS) as an innovative, safe, and cost-effective treatment for alcohol and other substance use disorders. A new review article by Antonello Bonci, M.D., of the National Institute on Drug Abuse (NIDA), with Lorenzo Leggio, M.D., Ph.D., of the National Institute on Alcohol Abuse and Alcoholism … Read more

NIAAA Scientists Provide More Evidence that Binge Drinking May Indicate Vulnerability to Alcohol Use Disorder

An NIAAA study shows that people who drink socially and have certain risk factors for alcohol use disorder (AUD) self-administer more alcohol and at a faster rate during a single laboratory session of alcohol consumption than people at low risk for developing AUD. Participants with all three risk factors evaluated in this study—being male, having … Read more