Study Shows Gene Editing May Hold Promise for Reversing Effects of Adolescent Binge Drinking

Gene editing could one day help reverse anxiety and excessive drinking caused by adolescent exposure to alcohol, according to a new study in rats supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). A team of investigators led by NIAAA grantee Subhash C. Pandey, Ph.D., the Joseph A. Flaherty-endowed professor of psychiatry and director of … Read more

Brain Research: A Focus on Childhood Trauma and Alcohol Misuse

News reports of college drinking tragedies, and concerns about increased access to alcohol in the home during the pandemic, make clear that COVID-19 has provided no reprieve from the problems of underage drinking. A perennial public health priority, alcohol misuse by young people increases the likelihood of myriad serious consequences, including altered brain development, academic … Read more

SBIRT Has Broad Impact on Adolescent Health

Over the last two decades, numerous research studies have firmly established the effectiveness of screening, brief intervention, and referral to treatment (SBIRT) in pediatric practices for alcohol and other substances in reducing underage drinking and its harmful consequences. More recently, investigators have hypothesized that SBIRT might have broader effects on adolescent health. Alcohol and other … Read more

NIH-funded rodent study finds molecular link between adolescent alcohol use and adult anxiety

Wine glass and beer bottle over brain graphic

New preclinical research in rats has identified a link between adolescent alcohol exposure and specific molecular changes in the brain that contribute to increased anxiety in adulthood. A large body of evidence demonstrates a strong relationship between alcohol and anxiety problems in humans. “These findings provide insight into the mechanisms through which alcohol-induced brain changes … Read more

Advances in Understanding and Addressing Underage Drinking

Combating underage drinking is a major public health priority, as alcohol use by young people increases the likelihood of short- and long-term consequences, including altered brain development, academic problems, sexually transmitted infections, physical and sexual assault, traffic crashes, injuries, overdoses, and alcohol use disorder (AUD). Epidemiological data from the 2018 Monitoring the Future (MTF) survey, … Read more