Scientists discover brain cells that compete to sustain or suppress traumatic memories

Two clusters of brain cells compete to promote either the persistence or disappearance of traumatic memories, according to a new study conducted in mice. The findings could provide important insights into human conditions such as post-traumatic stress disorder (PTSD), anxiety disorders, and associated problems such as alcohol use disorder (AUD) that can arise from the … Read more

Insights on Alcohol-Related Brain Inflammation, and Hints About How to Reduce It

Research suggests that long-term alcohol exposure leads to inflammation and damage to tissue in the brain and other organs—and inflammation could also potentially be involved in alcohol use disorder (AUD). A recently published mouse study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) suggests a mechanism that contributes to this process: the migration and … Read more

Emotional Responses to Alcohol May Predict Alcohol-Related Problems

Alcohol can induce temporary positive feelings such as elation and happiness and reduce negative feelings like distress. These emotional responses to alcohol are believed to contribute to drinking behaviors that lead to alcohol use disorder or that make abstaining from drinking more difficult for some people. A new study funded by the National Institute on … Read more

Brain Research: A Focus on Childhood Trauma and Alcohol Misuse

News reports of college drinking tragedies, and concerns about increased access to alcohol in the home during the pandemic, make clear that COVID-19 has provided no reprieve from the problems of underage drinking. A perennial public health priority, alcohol misuse by young people increases the likelihood of myriad serious consequences, including altered brain development, academic … Read more

NESARC-III genetic data now available to researchers

The NIAAA announces the release of genetic data collected from individuals who participated in NIAAA’s National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III), the largest study ever conducted on alcohol use and alcohol use disorder (AUD), and its co-occurrence with drug use, substance use disorders (SUD), and related psychiatric conditions. The NESARC-III is a … Read more