NIH-funded rodent study finds molecular link between adolescent alcohol use and adult anxiety

Wine glass and beer bottle over brain graphic

New preclinical research in rats has identified a link between adolescent alcohol exposure and specific molecular changes in the brain that contribute to increased anxiety in adulthood. A large body of evidence demonstrates a strong relationship between alcohol and anxiety problems in humans. “These findings provide insight into the mechanisms through which alcohol-induced brain changes … Read more

NIH study of brain energy patterns provides new insights into alcohol effects

Image of brain scans

Assessing the patterns of energy use and neuronal activity simultaneously in the human brain improves our understanding of how alcohol affects the brain, according to new research by scientists at the National Institutes of Health. The new approach for characterizing brain energetic patterns could also be useful for studying other neuropsychiatric diseases. A report of … Read more

Advancing Alcoholic Hepatitis Research

Breakthroughs in neuroscience have firmly established our understanding of alcohol use disorder (AUD) as a chronic brain disease. But when it comes to the adverse health effects of alcohol, the brain is not the only game in town. Drinking too much—on a single occasion or over time—can take a serious toll on just about every … Read more

Advances in Understanding and Addressing Underage Drinking

Combating underage drinking is a major public health priority, as alcohol use by young people increases the likelihood of short- and long-term consequences, including altered brain development, academic problems, sexually transmitted infections, physical and sexual assault, traffic crashes, injuries, overdoses, and alcohol use disorder (AUD). Epidemiological data from the 2018 Monitoring the Future (MTF) survey, … Read more

Prenatal Choline May Ameliorate Effects of Prenatal Alcohol Exposure

Prenatal supplements with the nutrient choline may help protect against alcohol-related deficits in children born to women who drink alcohol during pregnancy, according to a small clinical trial supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The new findings were reported in the July 2018 issue of Alcoholism: Clinical and Experimental Research. Choline … Read more

Maternal Cytokine Balance May Play Role in FASD Risk

A study done in conjunction with the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), which is supported by the National Institute on Alcohol Abuse and Alcoholism, reports that disruptions in levels of certain immune system molecules during pregnancy can alter the risk for fetal alcohol spectrum disorders (FASD). The effects of alcohol consumption on the … Read more