Bacteriophage therapy may ease severity of alcoholic hepatitis

NIH-funded study in mice merits further investigation as a potential treatment A specific strain of a common bacteria found in most people with alcoholic hepatitis correlates with greater liver disease severity and mortality, according to a new study published in Nature. Alcoholic hepatitis is a serious form of alcohol-associated liver disease, and people with it … Read more

Using both marijuana and alcohol during early pregnancy may increase the likelihood of disrupting fetal development

New preclinical research reported in animal models shows that exposure to compounds found in marijuana called cannabinoids (CBs), which includes cannabidiol (CBD) and tetrahydrocannabinol (THC), during early pregnancy can cause malformations in the developing embryo. The research also demonstrated that co-exposure to CBs and alcohol increased the likelihood of birth defects involving the face and … Read more

The Complex Relationship Between Alcohol and Pain

The relationship between alcohol and pain is a complicated one. It is a common belief that alcohol dulls pain, yet research shows that sometimes alcohol can make pain worse. Understanding the complex relationship between alcohol and pain is an important area of research for the National Institute on Alcohol Abuse and Alcoholism (NIAAA). In 2016, … Read more

Alcohol and “Deaths of Despair”

In 2015, Princeton University economists Anne Case, Ph.D., and Angus Deaton, Ph.D., reported something unexpected. After decreasing since the end of World War II, rates of death began to increase in the United States for people in some groups. The rise in deaths was driven primarily by drug and alcohol overdoses, suicides, and liver disease. … Read more

New preclinical study points to potential role of human gene in addiction

A new study led by researchers at the National Institute and Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), identifies regions of the rat genome that are associated with a behavior that is highly predictive of addiction onset and progression. The region in the rat genome with the strongest association … Read more

Integrated stepped alcohol treatment for people in HIV care improves both HIV and alcohol outcomes

New clinical research supported by the National Institutes of Health shows that increasing the intensity of treatment for alcohol use disorder (AUD) over time improves alcohol-related outcomes among people with HIV. This stepped approach to AUD treatment also improves HIV-related disease measures in this patient population.  A report of the new study, led by researchers … Read more

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