Scientists Find Brain Pathways for Threat Response in Mice

Scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) have identified brain pathways that may coordinate an animal’s response to potentially traumatic situations. Understanding where and how neural circuits mediate such functions—and how they could malfunction—may provide clues about their role in trauma-related and stress-related psychiatric disorders in people. A report of this … Read more

National Institute on Alcohol Abuse and Alcoholism Launches an Educational Virtual Reality Experience for Teens

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) recently launched Alcohol and Your Brain, a virtual reality (VR) module to engage and educate young audiences about how alcohol affects the brain. Designed for Oculus Quest, Quest 2, or Meta Quest Pro headsets, this activity takes users on a virtual rollercoaster ride through the brain, with … Read more

Study Shows Gene Editing May Hold Promise for Reversing Effects of Adolescent Binge Drinking

Gene editing could one day help reverse anxiety and excessive drinking caused by adolescent exposure to alcohol, according to a new study in rats supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). A team of investigators led by NIAAA grantee Subhash C. Pandey, Ph.D., the Joseph A. Flaherty-endowed professor of psychiatry and director of … Read more

Scientists discover brain cells that compete to sustain or suppress traumatic memories

Two clusters of brain cells compete to promote either the persistence or disappearance of traumatic memories, according to a new study conducted in mice. The findings could provide important insights into human conditions such as post-traumatic stress disorder (PTSD), anxiety disorders, and associated problems such as alcohol use disorder (AUD) that can arise from the … Read more

Insights on Alcohol-Related Brain Inflammation, and Hints About How to Reduce It

Research suggests that long-term alcohol exposure leads to inflammation and damage to tissue in the brain and other organs—and inflammation could also potentially be involved in alcohol use disorder (AUD). A recently published mouse study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) suggests a mechanism that contributes to this process: the migration and … Read more

Brain Research: A Focus on Childhood Trauma and Alcohol Misuse

News reports of college drinking tragedies, and concerns about increased access to alcohol in the home during the pandemic, make clear that COVID-19 has provided no reprieve from the problems of underage drinking. A perennial public health priority, alcohol misuse by young people increases the likelihood of myriad serious consequences, including altered brain development, academic … Read more