Deaths involving alcohol increased during the COVID-19 pandemic

Recently researchers at NIAAA used the national death certificate database to assess changes in alcohol-related deaths during the first year of the pandemic. The results, published in JAMA, show that after increasing around 2.2% per year over the previous two decades, deaths involving alcohol jumped 25.5% between 2019 to 2020, totaling 99,107 deaths.1 The study showed … Read more

Alcohol Rehabilitation Can Reduce Hospital Readmission, Relapse, and Mortality in Patients with Alcoholic Hepatitis

Early alcohol rehabilitation can reduce the risk of hospital readmission, alcohol relapse, and mortality among patients hospitalized for alcoholic hepatitis (AH), according to a recent National Institute on Alcohol Abuse and Alcoholism (NIAAA) supported study. AH is a potentially life-threatening alcohol-associated liver disease; many patients who are hospitalized with severe cases of AH die within … Read more

Bacteriophage therapy may ease severity of alcoholic hepatitis

NIH-funded study in mice merits further investigation as a potential treatment A specific strain of a common bacteria found in most people with alcoholic hepatitis correlates with greater liver disease severity and mortality, according to a new study published in Nature. Alcoholic hepatitis is a serious form of alcohol-associated liver disease, and people with it … Read more

Alcohol and “Deaths of Despair”

In 2015, Princeton University economists Anne Case, Ph.D., and Angus Deaton, Ph.D., reported something unexpected. After decreasing since the end of World War II, rates of death began to increase in the United States for people in some groups. The rise in deaths was driven primarily by drug and alcohol overdoses, suicides, and liver disease. … Read more

A New Treatment Strategy for Alcohol-Associated Liver Disease

Alcohol is involved in nearly half of all liver disease deaths in the United States each year. Alcohol-associated liver disease (AALD) now replaces hepatitis C viral infection as the lead cause of liver transplantation due to chronic liver disease. Consequently, there is an urgent need for effective interventions for AALD, a complex disease with multiple … Read more

Advancing Alcoholic Hepatitis Research

Breakthroughs in neuroscience have firmly established our understanding of alcohol use disorder (AUD) as a chronic brain disease. But when it comes to the adverse health effects of alcohol, the brain is not the only game in town. Drinking too much—on a single occasion or over time—can take a serious toll on just about every … Read more