Hunger Hormone Affects Alcohol Intake

X-ray of human body

A new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) provides further evidence that a hormone produced in the stomach influences alcohol consumption in humans. As reported in Molecular Psychiatry, researchers led by Lorenzo Leggio, M.D., Ph.D., demonstrated that the hormone, called ghrelin, may be a promising target for developing … Read more

MicroRNAs May Have Therapeutic Potential for Alcohol-Induced Liver Injury

Picture of DNA strand

MicroRNAs, or miRNAs, are short strands of RNA that play important roles in gene regulation. In two recent studies, researchers supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) identified two miRNAs that may help protect against alcohol-induced liver injury. Paramananda Saikia, Ph.D., and colleagues at the Cleveland Clinic, in studies conducted in … Read more

Behavioral Interventions That Address Alcohol Use Help People Living With HIV/AIDS

Doctor speaking to a patient

There are more than 36 million people living with HIV/AIDS (PLWHA) worldwide. Alcohol misuse is a significant concern for this population because it contributes to risky sexual behavior, reduces adherence to HIV medication regimens, and exacerbates other health conditions. Interventions that address alcohol misuse among PLWHA have the potential to help improve their health outcomes. … Read more

Rehabilitating the Addicted Brain With Transcranial Magnetic Stimulation

Recent studies have highlighted the potential of transcranial magnetic stimulation (TMS) as an innovative, safe, and cost-effective treatment for alcohol and other substance use disorders. A new review article by Antonello Bonci, M.D., of the National Institute on Drug Abuse (NIDA), with Lorenzo Leggio, M.D., Ph.D., of the National Institute on Alcohol Abuse and Alcoholism … Read more

Brain Studies Point to Perils of Adolescent Alcohol Use

Image of a brain

The brain takes longer to develop and mature than any other organ in the body. Beginning in the third week of gestation and extending into the mid-20s, an ongoing interplay of genetic and environmental factors results in the mature human brain, a structure composed of more than 100 billion neurons. Some of the most rapid … Read more

New Prevalence Estimates of Fetal Alcohol Spectrum Disorders Range From 1 to 5 Percent in U.S. Communities

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Findings reflect a more comprehensive approach and larger sample size than previous studies A study of more than 6,000 first-graders across 4 U.S. communities has found that a significant number of children have fetal alcohol spectrum disorders (FASD), with conservative rates ranging from 1 to 5 percent in community samples. The new findings represent more … Read more