Study Shows Gene Editing May Hold Promise for Reversing Effects of Adolescent Binge Drinking

Gene editing could one day help reverse anxiety and excessive drinking caused by adolescent exposure to alcohol, according to a new study in rats supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). A team of investigators led by NIAAA grantee Subhash C. Pandey, Ph.D., the Joseph A. Flaherty-endowed professor of psychiatry and director of … Read more

Study Suggests Possible Dietary Treatment for Alcohol Withdrawal Symptoms

A diet high in fat and low in carbohydrates and protein, known as a ketogenic diet, may help reduce the severity of alcohol withdrawal symptoms in people being treated for alcohol use disorder (AUD), according to a new study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National … Read more

Alcohol and Marijuana Use and Motivations Among Young Adults During the Pandemic

Stay-at-home and physical distancing orders during the COVID-19 pandemic have led to increased stress, anxiety, depression, and boredom, and reports suggest that some people may be consuming more alcohol as a coping mechanism. A recent study supported by the National Institute on Alcohol Abuse and Alcoholism now reveals changes in patterns of alcohol and marijuana … Read more

Insights on Alcohol-Related Brain Inflammation, and Hints About How to Reduce It

Research suggests that long-term alcohol exposure leads to inflammation and damage to tissue in the brain and other organs—and inflammation could also potentially be involved in alcohol use disorder (AUD). A recently published mouse study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) suggests a mechanism that contributes to this process: the migration and … Read more

Emotional Responses to Alcohol May Predict Alcohol-Related Problems

Alcohol can induce temporary positive feelings such as elation and happiness and reduce negative feelings like distress. These emotional responses to alcohol are believed to contribute to drinking behaviors that lead to alcohol use disorder or that make abstaining from drinking more difficult for some people. A new study funded by the National Institute on … Read more

Abstinence May Influence Changes in the Gut Microbiome of People With Alcohol Use Disorder

Chronic heavy drinking, a common symptom of alcohol use disorder (AUD), has been linked to changes in the levels and types of beneficial bacteria in the gut, known as the gut microbiome. Changes in the gut microbiome, often termed microbial dysbiosis, can lead to further downstream health problems such as liver disease, inflammation, and malnutrition. … Read more